The under-eye area is often the first place patients notice signs of aging. Dark circles, hollowing, fine lines, and crepey skin can make you look tired—even when you feel your best.
Two of the most effective treatments for restoring a refreshed under-eye appearance are PRFM (Platelet-Rich Fibrin Matrix) and under-eye dermal filler. But which one is right for you?
The answer depends on your anatomy, concerns, and goals.
At MediFreda, we often use both treatments strategically—because under-eye rejuvenation isn’t one-size-fits-all.
Let’s break down the difference.
What Is PRFM for Under Eyes?
PRFM is a regenerative treatment made from your own blood. It contains platelets, fibrin, stem cells, and growth factors that stimulate collagen production and improve skin quality over time.
Instead of simply filling the area, PRFM helps the skin repair itself.
PRFM is ideal for improving:
• dark circles
• thin under-eye skin
• fine lines
• crepey texture
• mild hollowing
• overall skin brightness
Because it releases growth factors gradually, results develop naturally over several weeks.
What Is Under-Eye Filler?
Under-eye filler uses hyaluronic acid to restore lost volume beneath the eyes. It smooths the transition between the lower eyelid and cheek, instantly reducing shadowing and hollowness.
It works best for:
• tear trough hollowing
• volume loss
• shadowing from structural deficiency
• contour irregularities between eyelid and cheek
Unlike PRFM, filler produces immediate improvement after treatment.
The Biggest Difference Between PRFM and Under-Eye Filler
Think of it this way:
PRFM improves the skin.
Filler improves the structure.
PRFM stimulates collagen and thickens delicate under-eye tissue over time, while filler restores lost support instantly.
That’s why the best treatment depends on what’s actually causing your under-eye concern.
How Long Do Results Last?
PRFM results typically last about 6–12 months, depending on the patient and number of sessions.
Under-eye filler results usually last 6–18 months, depending on the product used and metabolism.
Many patients benefit from a combination approach for longer-lasting improvement.
Which Treatment Looks More Natural?
Both treatments can look natural when performed correctly.
However:
• PRFM creates gradual, subtle improvement
• filler creates faster structural correction
• PRFM carries virtually no risk of allergic reaction because it uses your own blood
• filler requires precise placement due to the delicate anatomy of the under-eye area
For patients worried about puffiness or overfilling, PRFM is often the safer starting point.
When PRFM Is the Better Choice
PRFM is usually ideal if you notice:
• dark circles from thin skin
• crepey texture
• early aging changes
• mild hollowing
• poor skin quality under the eyes
• a preference for natural treatments
It improves the skin itself—not just the appearance.
What Is Selphyller® Gel?
Selphyller® Gel is an advanced form of PRFM that is processed into a smooth injectable “bio-filler” using your body’s own regenerative material.
It provides subtle volume while also improving skin quality—making it a natural bridge between PRFM and traditional filler.
Selphyller® Gel is ideal for improving:
• mild to moderate tear trough hollowing
• thin under-eye skin
• dark circles related to translucency
• early volume loss
• crepey texture
Because it stimulates collagen while restoring gentle support, results appear natural and continue improving over time.
When Under-Eye Filler Is the Better Choice
Filler is often the better option if you have:
• moderate to deep tear troughs
• structural volume loss
• shadowing from cheek support deficiency
• strong midface hollowing
In these cases, restoring structure creates the biggest improvement.
Can PRFM and Under-Eye Filler Be Combined?
Yes—and this is often the most effective strategy.
PRFM improves skin thickness and brightness, while filler restores contour support. Together, they create smoother, healthier-looking under-eyes without looking overdone.
At MediFreda, combination treatments are frequently used to achieve the most natural results.
So, Which Treatment Is Better?
Neither treatment is universally “better.”
The best option depends on whether your concern is skin quality, volume loss, or both.
PRFM is ideal for regeneration and subtle rejuvenation.
Filler is ideal for structural correction and immediate improvement.
During a consultation, we evaluate the entire midface—not just the under-eye area—to determine the safest and most natural approach for each patient.
Because refreshed under-eyes shouldn’t look treated—they should just look like you slept well.





